Which prefix means "above" or "upon"?

The prefix that means "above" or "upon" is "epi-." This prefix is commonly used in medical terminology to indicate a position that is situated over or upon something else. For instance, in terms like "epidermis," it refers to the outer layer of skin that lies above the underlying layers.

Understanding this prefix is crucial in comprehending the specific locations of structures in anatomy and their relationships to one another. In a medical context, using "epi-" helps to create clarity in discussions regarding physical anatomy or pathology.

The other prefixes indicate different meanings: "super-" also conveys a sense of "above" but more in a quantitative or superior sense; "infra-" means "below" or "beneath," while "trans-" indicates movement across or through something. Each of these prefixes serves a unique purpose in medical terminology, emphasizing the importance of selecting the correct one for accurate communication.